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Restriction enzymes use a 24 dimensional coding space to recognize 6 base long DNA sequences

Restriction enzymes recognize and bind to specific sequences on invading bacteriophage DNA. Like a key in a lock, these proteins require many contacts to specify the correct DNA sequence. Using information theory we develop an equation that defines the number of independent contacts, which is the di...

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Detalles Bibliográficos
Autores principales: Schneider, Thomas D., Jejjala, Vishnu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822723/
https://www.ncbi.nlm.nih.gov/pubmed/31671158
http://dx.doi.org/10.1371/journal.pone.0222419