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Endothelial nitric oxide synthase limits host immunity to control disseminated Candida albicans infections in mice

Three isoforms of nitric oxide synthase (NOS) occur in mammals. High levels of NO produced by NOS2/iNOS can protect against bacterial and parasitic infections, but the role of NOS in fungal innate immunity is less clear. Compared to wild type mice, Nos3(-/-) mice showed significantly higher survival...

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Detalles Bibliográficos
Autores principales:	Navarathna, Dhammika H., Lionakis, Michail S., Roberts, David D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822743/ https://www.ncbi.nlm.nih.gov/pubmed/31671151 http://dx.doi.org/10.1371/journal.pone.0223919

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