High-throughput micropatterning platform reveals Nodal-dependent bisection of peri-gastrulation–associated versus preneurulation-associated fate patterning

In vitro models of postimplantation human development are valuable to the fields of regenerative medicine and developmental biology. Here, we report characterization of a robust in vitro platform that enabled high-content screening of multiple human pluripotent stem cell (hPSC) lines for their abili...

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Detalles Bibliográficos
Autores principales: Tewary, Mukul, Dziedzicka, Dominika, Ostblom, Joel, Prochazka, Laura, Shakiba, Nika, Heydari, Tiam, Aguilar-Hidalgo, Daniel, Woodford, Curtis, Piccinini, Elia, Becerra-Alonso, David, Vickers, Alice, Louis, Blaise, Rahman, Nafees, Danovi, Davide, Geens, Mieke, Watt, Fiona M., Zandstra, Peter W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822778/
https://www.ncbi.nlm.nih.gov/pubmed/31634368
http://dx.doi.org/10.1371/journal.pbio.3000081

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