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Pharmacokinetics of Total and Unbound Paclitaxel After Administration of Paclitaxel Micellar or Nab-Paclitaxel: An Open, Randomized, Cross-Over, Explorative Study in Breast Cancer Patients

INTRODUCTION: Paclitaxel micellar is a novel formulation of paclitaxel in which retinoic acid derivates solubilize paclitaxel. The aim of the present study was to compare the unbound and total plasma pharmacokinetics of the new formulation with those of nanoparticle albumin-bound (nab)-paclitaxel an...

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Detalles Bibliográficos
Autores principales: Borgå, Olof, Lilienberg, Elsa, Bjermo, Helena, Hansson, Fredrik, Heldring, Nina, Dediu, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822820/
https://www.ncbi.nlm.nih.gov/pubmed/31432461
http://dx.doi.org/10.1007/s12325-019-01058-6