Neuromyelitis Optica Spectrum Disorder: A Rare Case of Isolated Brainstem Syndrome

Before 2006, neuromyelitis optica was hallmarked by optic neuritis and transverse myelitis. However, with the discovery of antibodies to water channel aquaporin-4 as a diagnostic criterion, our clinical knowledge of the disease manifested in the creation of new pathologies that fell under the diagno...

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Autores principales: Bui, Mai-Lynn, Gould, Jordan K, Mentreddy, Akshay, Sigsbee, Emily, Lalama, Hector
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822874/
https://www.ncbi.nlm.nih.gov/pubmed/31700746
http://dx.doi.org/10.7759/cureus.5644
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author Bui, Mai-Lynn
Gould, Jordan K
Mentreddy, Akshay
Sigsbee, Emily
Lalama, Hector
author_facet Bui, Mai-Lynn
Gould, Jordan K
Mentreddy, Akshay
Sigsbee, Emily
Lalama, Hector
author_sort Bui, Mai-Lynn
collection PubMed
description Before 2006, neuromyelitis optica was hallmarked by optic neuritis and transverse myelitis. However, with the discovery of antibodies to water channel aquaporin-4 as a diagnostic criterion, our clinical knowledge of the disease manifested in the creation of new pathologies that fell under the diagnostic umbrella of neuromyelitis optica spectrum disorder (NMOSD). Still, brain involvement of the disease has remained rare, in particular, lesions of the brain stem. Specific to our report is a novel case of NMOSD with intriguing, isolated brainstem findings.
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spelling pubmed-68228742019-11-07 Neuromyelitis Optica Spectrum Disorder: A Rare Case of Isolated Brainstem Syndrome Bui, Mai-Lynn Gould, Jordan K Mentreddy, Akshay Sigsbee, Emily Lalama, Hector Cureus Neurology Before 2006, neuromyelitis optica was hallmarked by optic neuritis and transverse myelitis. However, with the discovery of antibodies to water channel aquaporin-4 as a diagnostic criterion, our clinical knowledge of the disease manifested in the creation of new pathologies that fell under the diagnostic umbrella of neuromyelitis optica spectrum disorder (NMOSD). Still, brain involvement of the disease has remained rare, in particular, lesions of the brain stem. Specific to our report is a novel case of NMOSD with intriguing, isolated brainstem findings. Cureus 2019-09-13 /pmc/articles/PMC6822874/ /pubmed/31700746 http://dx.doi.org/10.7759/cureus.5644 Text en Copyright © 2019, Bui et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurology
Bui, Mai-Lynn
Gould, Jordan K
Mentreddy, Akshay
Sigsbee, Emily
Lalama, Hector
Neuromyelitis Optica Spectrum Disorder: A Rare Case of Isolated Brainstem Syndrome
title Neuromyelitis Optica Spectrum Disorder: A Rare Case of Isolated Brainstem Syndrome
title_full Neuromyelitis Optica Spectrum Disorder: A Rare Case of Isolated Brainstem Syndrome
title_fullStr Neuromyelitis Optica Spectrum Disorder: A Rare Case of Isolated Brainstem Syndrome
title_full_unstemmed Neuromyelitis Optica Spectrum Disorder: A Rare Case of Isolated Brainstem Syndrome
title_short Neuromyelitis Optica Spectrum Disorder: A Rare Case of Isolated Brainstem Syndrome
title_sort neuromyelitis optica spectrum disorder: a rare case of isolated brainstem syndrome
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822874/
https://www.ncbi.nlm.nih.gov/pubmed/31700746
http://dx.doi.org/10.7759/cureus.5644
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