Cargando…

Stem Cell Therapies: A Way to Promising Cures

Stem cells carry the remarkable ability to differentiate into different cell types while retaining the capability to self-replicate and maintain the characteristics of their parent cells, referred to as potency. Stem cells have been studied extensively to better understand human development and orga...

Descripción completa

Detalles Bibliográficos
Autores principales: Nawab, Khalid, Bhere, Deepak, Bommarito, Anthony, Mufti, Muhammad, Naeem, Awais
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823091/
https://www.ncbi.nlm.nih.gov/pubmed/31720180
http://dx.doi.org/10.7759/cureus.5712
_version_ 1783464473372131328
author Nawab, Khalid
Bhere, Deepak
Bommarito, Anthony
Mufti, Muhammad
Naeem, Awais
author_facet Nawab, Khalid
Bhere, Deepak
Bommarito, Anthony
Mufti, Muhammad
Naeem, Awais
author_sort Nawab, Khalid
collection PubMed
description Stem cells carry the remarkable ability to differentiate into different cell types while retaining the capability to self-replicate and maintain the characteristics of their parent cells, referred to as potency. Stem cells have been studied extensively to better understand human development and organogenesis. Because of advances in stem cell-based therapies, regenerative medicine has seen significant growth. Ophthalmic conditions, some of which are leading causes of blindness worldwide, are being treated with stem cell therapies. Great results have also been obtained in the treatment of oral and maxillofacial defects. Stem-cell-based therapies have great potential in the treatment of chronic medical conditions like diabetes and cardiomyopathy. The unique property of stem cells to migrate towards cancer cells makes them excellent vectors for the transportation of bioactive agents or for targeting cancer cells, both primary and metastatic. While these therapeutic strategies are extremely promising, they are not without limitations. Failure to completely eradicate the tumor and tumor relapse are some of those concerns. Stem cells share some characteristics with cancer stem cells, raising concerns for increasing the risk of cancer occurrence. Ethical concerns due to the fetal origin of stem cells and cost are other major obstacles in the large-scale implementation of such therapies.
format Online
Article
Text
id pubmed-6823091
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-68230912019-11-12 Stem Cell Therapies: A Way to Promising Cures Nawab, Khalid Bhere, Deepak Bommarito, Anthony Mufti, Muhammad Naeem, Awais Cureus Internal Medicine Stem cells carry the remarkable ability to differentiate into different cell types while retaining the capability to self-replicate and maintain the characteristics of their parent cells, referred to as potency. Stem cells have been studied extensively to better understand human development and organogenesis. Because of advances in stem cell-based therapies, regenerative medicine has seen significant growth. Ophthalmic conditions, some of which are leading causes of blindness worldwide, are being treated with stem cell therapies. Great results have also been obtained in the treatment of oral and maxillofacial defects. Stem-cell-based therapies have great potential in the treatment of chronic medical conditions like diabetes and cardiomyopathy. The unique property of stem cells to migrate towards cancer cells makes them excellent vectors for the transportation of bioactive agents or for targeting cancer cells, both primary and metastatic. While these therapeutic strategies are extremely promising, they are not without limitations. Failure to completely eradicate the tumor and tumor relapse are some of those concerns. Stem cells share some characteristics with cancer stem cells, raising concerns for increasing the risk of cancer occurrence. Ethical concerns due to the fetal origin of stem cells and cost are other major obstacles in the large-scale implementation of such therapies. Cureus 2019-09-20 /pmc/articles/PMC6823091/ /pubmed/31720180 http://dx.doi.org/10.7759/cureus.5712 Text en Copyright © 2019, Nawab et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Nawab, Khalid
Bhere, Deepak
Bommarito, Anthony
Mufti, Muhammad
Naeem, Awais
Stem Cell Therapies: A Way to Promising Cures
title Stem Cell Therapies: A Way to Promising Cures
title_full Stem Cell Therapies: A Way to Promising Cures
title_fullStr Stem Cell Therapies: A Way to Promising Cures
title_full_unstemmed Stem Cell Therapies: A Way to Promising Cures
title_short Stem Cell Therapies: A Way to Promising Cures
title_sort stem cell therapies: a way to promising cures
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823091/
https://www.ncbi.nlm.nih.gov/pubmed/31720180
http://dx.doi.org/10.7759/cureus.5712
work_keys_str_mv AT nawabkhalid stemcelltherapiesawaytopromisingcures
AT bheredeepak stemcelltherapiesawaytopromisingcures
AT bommaritoanthony stemcelltherapiesawaytopromisingcures
AT muftimuhammad stemcelltherapiesawaytopromisingcures
AT naeemawais stemcelltherapiesawaytopromisingcures