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Very Early Continence After Radical Prostatectomy and Its Influencing Factors

Introduction and Objectives: Surgical techniques such as preservation of the full functional-length of the urethral sphincter (FFLU) have a positive impact on postoperative continence rates. Thereby, data on very early continence rates after radical prostatectomy (RP) are scarce. The aim of the pres...

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Autores principales: Theissen, Lena, Preisser, Felix, Wenzel, Mike, Humke, Clara, Roos, Frederik C., Kluth, Luis A., Becker, Andreas, Banek, Severine, Bodelle, Boris, Köllermann, Jens, Chun, Felix K. H., Mandel, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823177/
https://www.ncbi.nlm.nih.gov/pubmed/31709260
http://dx.doi.org/10.3389/fsurg.2019.00060
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author Theissen, Lena
Preisser, Felix
Wenzel, Mike
Humke, Clara
Roos, Frederik C.
Kluth, Luis A.
Becker, Andreas
Banek, Severine
Bodelle, Boris
Köllermann, Jens
Chun, Felix K. H.
Mandel, Philipp
author_facet Theissen, Lena
Preisser, Felix
Wenzel, Mike
Humke, Clara
Roos, Frederik C.
Kluth, Luis A.
Becker, Andreas
Banek, Severine
Bodelle, Boris
Köllermann, Jens
Chun, Felix K. H.
Mandel, Philipp
author_sort Theissen, Lena
collection PubMed
description Introduction and Objectives: Surgical techniques such as preservation of the full functional-length of the urethral sphincter (FFLU) have a positive impact on postoperative continence rates. Thereby, data on very early continence rates after radical prostatectomy (RP) are scarce. The aim of the present study was to analyze very early continence rates in patients undergoing FFLU during RP. Materials and Methods: Very early-continence was assessed by using the PAD-test within 24 h after removal of the transurethral catheter. The PAD-test is a validated test that measures the amount of involuntary urine loss while performing predefined physical activities within 1 h (e.g., coughing, walking, climbing stairs). Full continence was defined as a urine loss below 1 g. Mild, moderate, and severe incontinence was defined as urine loss of 1–10 g, 11–50 g, and >50 g, respectively. Results: 90 patients were prospectively analyzed. Removal of the catheter was performed on the 6th postoperative day. Proportions for no, mild, moderate and severe incontinence were 18.9, 45.5, 20.0, and 15.6%, respectively. In logistic regression younger age was associated with significant better continence (HR 2.52, p = 0.04), while bilateral nerve-sparing (HR 2.56, p = 0.057) and organ-confined tumor (HR 2.22, p = 0.078) showed lower urine loss, although the effect was statistically not significant. In MVA, similar results were recorded. Conclusion: Overall, 64.4% of patients were continent or suffered only from mild incontinence at 24 h after catheter removal. In general, reduced urine loss was recorded in younger patients, patients with organ-confined tumor and in patients with bilateral nerve sparing. Severe incontinence rates were remarkably low with 15.6%.
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spelling pubmed-68231772019-11-08 Very Early Continence After Radical Prostatectomy and Its Influencing Factors Theissen, Lena Preisser, Felix Wenzel, Mike Humke, Clara Roos, Frederik C. Kluth, Luis A. Becker, Andreas Banek, Severine Bodelle, Boris Köllermann, Jens Chun, Felix K. H. Mandel, Philipp Front Surg Surgery Introduction and Objectives: Surgical techniques such as preservation of the full functional-length of the urethral sphincter (FFLU) have a positive impact on postoperative continence rates. Thereby, data on very early continence rates after radical prostatectomy (RP) are scarce. The aim of the present study was to analyze very early continence rates in patients undergoing FFLU during RP. Materials and Methods: Very early-continence was assessed by using the PAD-test within 24 h after removal of the transurethral catheter. The PAD-test is a validated test that measures the amount of involuntary urine loss while performing predefined physical activities within 1 h (e.g., coughing, walking, climbing stairs). Full continence was defined as a urine loss below 1 g. Mild, moderate, and severe incontinence was defined as urine loss of 1–10 g, 11–50 g, and >50 g, respectively. Results: 90 patients were prospectively analyzed. Removal of the catheter was performed on the 6th postoperative day. Proportions for no, mild, moderate and severe incontinence were 18.9, 45.5, 20.0, and 15.6%, respectively. In logistic regression younger age was associated with significant better continence (HR 2.52, p = 0.04), while bilateral nerve-sparing (HR 2.56, p = 0.057) and organ-confined tumor (HR 2.22, p = 0.078) showed lower urine loss, although the effect was statistically not significant. In MVA, similar results were recorded. Conclusion: Overall, 64.4% of patients were continent or suffered only from mild incontinence at 24 h after catheter removal. In general, reduced urine loss was recorded in younger patients, patients with organ-confined tumor and in patients with bilateral nerve sparing. Severe incontinence rates were remarkably low with 15.6%. Frontiers Media S.A. 2019-10-25 /pmc/articles/PMC6823177/ /pubmed/31709260 http://dx.doi.org/10.3389/fsurg.2019.00060 Text en Copyright © 2019 Theissen, Preisser, Wenzel, Humke, Roos, Kluth, Becker, Banek, Bodelle, Köllermann, Chun and Mandel. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Theissen, Lena
Preisser, Felix
Wenzel, Mike
Humke, Clara
Roos, Frederik C.
Kluth, Luis A.
Becker, Andreas
Banek, Severine
Bodelle, Boris
Köllermann, Jens
Chun, Felix K. H.
Mandel, Philipp
Very Early Continence After Radical Prostatectomy and Its Influencing Factors
title Very Early Continence After Radical Prostatectomy and Its Influencing Factors
title_full Very Early Continence After Radical Prostatectomy and Its Influencing Factors
title_fullStr Very Early Continence After Radical Prostatectomy and Its Influencing Factors
title_full_unstemmed Very Early Continence After Radical Prostatectomy and Its Influencing Factors
title_short Very Early Continence After Radical Prostatectomy and Its Influencing Factors
title_sort very early continence after radical prostatectomy and its influencing factors
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823177/
https://www.ncbi.nlm.nih.gov/pubmed/31709260
http://dx.doi.org/10.3389/fsurg.2019.00060
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