Specialized structural and functional roles of residues selectively conserved in subfamilies of the pleckstrin homology domain family

Homologous domains embedded in multidomain proteins of different domain architectures (DA) may exhibit subtle, but important, differences in their structure and function. Here, we consider two multidomain proteins, Arf nucleotide binding site opener (ARNO) and G protein‐coupled receptor kinase 2 (GR...

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Detalles Bibliográficos
Autores principales: Naveenkumar, Nagarajan, Sowdhamini, Ramanathan, Srinivasan, Narayanaswamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823287/
https://www.ncbi.nlm.nih.gov/pubmed/31436855
http://dx.doi.org/10.1002/2211-5463.12725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823287/
https://www.ncbi.nlm.nih.gov/pubmed/31436855
http://dx.doi.org/10.1002/2211-5463.12725

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