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Transcriptomics and proteomics reveal two waves of translational repression during the maturation of malaria parasite sporozoites

Plasmodium sporozoites are transmitted from infected mosquitoes to mammals, and must navigate the host skin and vasculature to infect the liver. This journey requires distinct proteomes. Here, we report the dynamic transcriptomes and proteomes of both oocyst sporozoites and salivary gland sporozoite...

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Detalles Bibliográficos
Autores principales: Lindner, Scott E., Swearingen, Kristian E., Shears, Melanie J., Walker, Michael P., Vrana, Erin N., Hart, Kevin J., Minns, Allen M., Sinnis, Photini, Moritz, Robert L., Kappe, Stefan H. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823429/
https://www.ncbi.nlm.nih.gov/pubmed/31673027
http://dx.doi.org/10.1038/s41467-019-12936-6