Plasticity of the Mycobacterium tuberculosis respiratory chain and its impact on tuberculosis drug development

The viability of Mycobacterium tuberculosis (Mtb) depends on energy generated by its respiratory chain. Cytochrome bc1-aa3 oxidase and type-2 NADH dehydrogenase (NDH-2) are respiratory chain components predicted to be essential, and are currently targeted for drug development. Here we demonstrate th...

Descripción completa

Detalles Bibliográficos
Autores principales: Beites, Tiago, O’Brien, Kathryn, Tiwari, Divya, Engelhart, Curtis A., Walters, Shaun, Andrews, Jenna, Yang, Hee-Jeong, Sutphen, Michelle L., Weiner, Danielle M., Dayao, Emmanuel K., Zimmerman, Matthew, Prideaux, Brendan, Desai, Prashant V., Masquelin, Thierry, Via, Laura E., Dartois, Véronique, Boshoff, Helena I., Barry, Clifton E., Ehrt, Sabine, Schnappinger, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823465/
https://www.ncbi.nlm.nih.gov/pubmed/31672993
http://dx.doi.org/10.1038/s41467-019-12956-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823465/
https://www.ncbi.nlm.nih.gov/pubmed/31672993
http://dx.doi.org/10.1038/s41467-019-12956-2

Ejemplares similares