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Genetic characterization of a novel picornavirus in Algerian bats: co-evolution analysis of bat-related picornaviruses
Bats are reservoirs of numerous zoonotic viruses. The Picornaviridae family comprises important pathogens which may infect both humans and animals. In this study, a bat-related picornavirus was detected from Algerian Minioptreus schreibersii bats for the first time in the country. Molecular analyses...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823487/ https://www.ncbi.nlm.nih.gov/pubmed/31673141 http://dx.doi.org/10.1038/s41598-019-52209-2 |
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author | Zeghbib, Safia Herczeg, Róbert Kemenesi, Gábor Zana, Brigitta Kurucz, Kornélia Urbán, Péter Madai, Mónika Földes, Fanni Papp, Henrietta Somogyi, Balázs Jakab, Ferenc |
author_facet | Zeghbib, Safia Herczeg, Róbert Kemenesi, Gábor Zana, Brigitta Kurucz, Kornélia Urbán, Péter Madai, Mónika Földes, Fanni Papp, Henrietta Somogyi, Balázs Jakab, Ferenc |
author_sort | Zeghbib, Safia |
collection | PubMed |
description | Bats are reservoirs of numerous zoonotic viruses. The Picornaviridae family comprises important pathogens which may infect both humans and animals. In this study, a bat-related picornavirus was detected from Algerian Minioptreus schreibersii bats for the first time in the country. Molecular analyses revealed the new virus originates to the Mischivirus genus. In the operational use of the acquired sequence and all available data regarding bat picornaviruses, we performed a co-evolutionary analysis of mischiviruses and their hosts, to authentically reveal evolutionary patterns within this genus. Based on this analysis, we enlarged the dataset, and examined the co-evolutionary history of all bat-related picornaviruses including their hosts, to effectively compile all possible species jumping events during their evolution. Furthermore, we explored the phylogeny association with geographical location, host-genus and host-species in both data sets. |
format | Online Article Text |
id | pubmed-6823487 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-68234872019-11-12 Genetic characterization of a novel picornavirus in Algerian bats: co-evolution analysis of bat-related picornaviruses Zeghbib, Safia Herczeg, Róbert Kemenesi, Gábor Zana, Brigitta Kurucz, Kornélia Urbán, Péter Madai, Mónika Földes, Fanni Papp, Henrietta Somogyi, Balázs Jakab, Ferenc Sci Rep Article Bats are reservoirs of numerous zoonotic viruses. The Picornaviridae family comprises important pathogens which may infect both humans and animals. In this study, a bat-related picornavirus was detected from Algerian Minioptreus schreibersii bats for the first time in the country. Molecular analyses revealed the new virus originates to the Mischivirus genus. In the operational use of the acquired sequence and all available data regarding bat picornaviruses, we performed a co-evolutionary analysis of mischiviruses and their hosts, to authentically reveal evolutionary patterns within this genus. Based on this analysis, we enlarged the dataset, and examined the co-evolutionary history of all bat-related picornaviruses including their hosts, to effectively compile all possible species jumping events during their evolution. Furthermore, we explored the phylogeny association with geographical location, host-genus and host-species in both data sets. Nature Publishing Group UK 2019-10-31 /pmc/articles/PMC6823487/ /pubmed/31673141 http://dx.doi.org/10.1038/s41598-019-52209-2 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Zeghbib, Safia Herczeg, Róbert Kemenesi, Gábor Zana, Brigitta Kurucz, Kornélia Urbán, Péter Madai, Mónika Földes, Fanni Papp, Henrietta Somogyi, Balázs Jakab, Ferenc Genetic characterization of a novel picornavirus in Algerian bats: co-evolution analysis of bat-related picornaviruses |
title | Genetic characterization of a novel picornavirus in Algerian bats: co-evolution analysis of bat-related picornaviruses |
title_full | Genetic characterization of a novel picornavirus in Algerian bats: co-evolution analysis of bat-related picornaviruses |
title_fullStr | Genetic characterization of a novel picornavirus in Algerian bats: co-evolution analysis of bat-related picornaviruses |
title_full_unstemmed | Genetic characterization of a novel picornavirus in Algerian bats: co-evolution analysis of bat-related picornaviruses |
title_short | Genetic characterization of a novel picornavirus in Algerian bats: co-evolution analysis of bat-related picornaviruses |
title_sort | genetic characterization of a novel picornavirus in algerian bats: co-evolution analysis of bat-related picornaviruses |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823487/ https://www.ncbi.nlm.nih.gov/pubmed/31673141 http://dx.doi.org/10.1038/s41598-019-52209-2 |
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