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Histone H3K9 Trimethylation Downregulates the Expression of Brain-Derived Neurotrophic Factor in the Dorsal Hippocampus and Impairs Memory Formation During Anaesthesia and Surgery
Brain-derived neurotrophic factor (BDNF) is essential for cognitive and memory functions. Abnormal BDNF expression in the central nervous system may impair these functions. Anaesthesia and surgery can induce perioperative neurocognitive disorders (PND). Clinical studies show that BDNF expression is...
Autores principales: | Wu, Tong, Sun, Xiao-Yu, Yang, Xiu, Liu, Le, Tong, Kun, Gao, Ya, Hao, Jing-Ru, Cao, Jing, Gao, Can |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823536/ https://www.ncbi.nlm.nih.gov/pubmed/31708739 http://dx.doi.org/10.3389/fnmol.2019.00246 |
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