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“Close-to-Release”: Spontaneous Bioorthogonal Uncaging Resulting from Ring-Closing Metathesis

[Image: see text] Bioorthogonal uncaging reactions offer versatile tools in chemical biology. In recent years, reactions have been developed to proceed efficiently under physiological conditions. We present herein an uncaging reaction that results from ring-closing metathesis (RCM). A caged molecule...

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Detalles Bibliográficos
Autores principales: Sabatino, Valerio, Rebelein, Johannes G., Ward, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823642/
https://www.ncbi.nlm.nih.gov/pubmed/31503474
http://dx.doi.org/10.1021/jacs.9b07193

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