Stroke detection with 3 different PET tracers

Stroke is a common cause of patient morbidity and mortality, being the fifth leading cause of death in the United States. Positron emission tomography (PET) is a proven tool for oncology patients, and may have utility in patients with stroke. We demonstrate findings of stroke incidentally detected o...

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Detalles Bibliográficos
Autores principales: Dundar, Ayca, Bold, Michael S., Agac, Busranur, Kendi, Ayse Tuba, Friedman, Saul N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Nuclear Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823742/
https://www.ncbi.nlm.nih.gov/pubmed/31695834
http://dx.doi.org/10.1016/j.radcr.2019.09.005
Descripción
Sumario:Stroke is a common cause of patient morbidity and mortality, being the fifth leading cause of death in the United States. Positron emission tomography (PET) is a proven tool for oncology patients, and may have utility in patients with stroke. We demonstrate findings of stroke incidentally detected on oncologic PET/CTs using (18)F-FDG, (11)C-Choline, and (68)Ga-DOTATATE radiotracers. Specifically, focal (11)C-Choline or (68)Ga-DOTATATE uptakes localized in areas of MRI confirmed ischemia, and paradoxically increased (18)F-FDG activity was visualized surrounding a region of hemorrhage, in different patients. These cases demonstrate that PET may have utility in evaluating patients with stroke based on flow dynamics, metabolic activity, and receptor expression.

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