Stroke detection with 3 different PET tracers

Stroke is a common cause of patient morbidity and mortality, being the fifth leading cause of death in the United States. Positron emission tomography (PET) is a proven tool for oncology patients, and may have utility in patients with stroke. We demonstrate findings of stroke incidentally detected o...

Descripción completa

Detalles Bibliográficos
Autores principales: Dundar, Ayca, Bold, Michael S., Agac, Busranur, Kendi, Ayse Tuba, Friedman, Saul N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Nuclear Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823742/
https://www.ncbi.nlm.nih.gov/pubmed/31695834
http://dx.doi.org/10.1016/j.radcr.2019.09.005
_version_ 1783464586978000896
author Dundar, Ayca
Bold, Michael S.
Agac, Busranur
Kendi, Ayse Tuba
Friedman, Saul N.
author_facet Dundar, Ayca
Bold, Michael S.
Agac, Busranur
Kendi, Ayse Tuba
Friedman, Saul N.
author_sort Dundar, Ayca
collection PubMed
description Stroke is a common cause of patient morbidity and mortality, being the fifth leading cause of death in the United States. Positron emission tomography (PET) is a proven tool for oncology patients, and may have utility in patients with stroke. We demonstrate findings of stroke incidentally detected on oncologic PET/CTs using (18)F-FDG, (11)C-Choline, and (68)Ga-DOTATATE radiotracers. Specifically, focal (11)C-Choline or (68)Ga-DOTATATE uptakes localized in areas of MRI confirmed ischemia, and paradoxically increased (18)F-FDG activity was visualized surrounding a region of hemorrhage, in different patients. These cases demonstrate that PET may have utility in evaluating patients with stroke based on flow dynamics, metabolic activity, and receptor expression.
format Online
Article
Text
id pubmed-6823742
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-68237422019-11-06 Stroke detection with 3 different PET tracers Dundar, Ayca Bold, Michael S. Agac, Busranur Kendi, Ayse Tuba Friedman, Saul N. Radiol Case Rep Nuclear Medicine Stroke is a common cause of patient morbidity and mortality, being the fifth leading cause of death in the United States. Positron emission tomography (PET) is a proven tool for oncology patients, and may have utility in patients with stroke. We demonstrate findings of stroke incidentally detected on oncologic PET/CTs using (18)F-FDG, (11)C-Choline, and (68)Ga-DOTATATE radiotracers. Specifically, focal (11)C-Choline or (68)Ga-DOTATATE uptakes localized in areas of MRI confirmed ischemia, and paradoxically increased (18)F-FDG activity was visualized surrounding a region of hemorrhage, in different patients. These cases demonstrate that PET may have utility in evaluating patients with stroke based on flow dynamics, metabolic activity, and receptor expression. Elsevier 2019-10-01 /pmc/articles/PMC6823742/ /pubmed/31695834 http://dx.doi.org/10.1016/j.radcr.2019.09.005 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Nuclear Medicine
Dundar, Ayca
Bold, Michael S.
Agac, Busranur
Kendi, Ayse Tuba
Friedman, Saul N.
Stroke detection with 3 different PET tracers
title Stroke detection with 3 different PET tracers
title_full Stroke detection with 3 different PET tracers
title_fullStr Stroke detection with 3 different PET tracers
title_full_unstemmed Stroke detection with 3 different PET tracers
title_short Stroke detection with 3 different PET tracers
title_sort stroke detection with 3 different pet tracers
topic Nuclear Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823742/
https://www.ncbi.nlm.nih.gov/pubmed/31695834
http://dx.doi.org/10.1016/j.radcr.2019.09.005
work_keys_str_mv AT dundarayca strokedetectionwith3differentpettracers
AT boldmichaels strokedetectionwith3differentpettracers
AT agacbusranur strokedetectionwith3differentpettracers
AT kendiaysetuba strokedetectionwith3differentpettracers
AT friedmansauln strokedetectionwith3differentpettracers

Ejemplares similares