Tentative identification of 20(S)-protopanaxadiol metabolites in human plasma and urine using ultra-performance liquid chromatography coupled with triple quadrupole time-of-flight mass spectrometry

BACKGROUND: 20(S)-Protopanaxadiol (PPD), the aglycone part of 20(S)-protopanaxadiol ginsenosides, possesses antidepressant activity among many other pharmacological activities. It is currently undergoing clinical trial in China as an antidepressant. METHODS: In this study, an ultra-performance liqui...

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Detalles Bibliográficos
Autores principales: Ling, Jin, Yu, Yingjia, Long, Jiakun, Li, Yan, Jiang, Jiebing, Wang, Liping, Xu, Changjiang, Duan, Gengli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823760/
https://www.ncbi.nlm.nih.gov/pubmed/31695562
http://dx.doi.org/10.1016/j.jgr.2018.03.005

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