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White matter repair and treatment strategy after intracerebral hemorrhage
The predilection site of intracerebral hemorrhage (ICH) is in the basal ganglia, which is rich in white matter (WM) fiber bundles, such as cerebrospinal tract in the internal capsule. ICH induced damage to this area can easily lead to severe neurological dysfunction and affects the prognosis and qua...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823871/ https://www.ncbi.nlm.nih.gov/pubmed/31578825 http://dx.doi.org/10.1111/cns.13226 |
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author | Jiang, Yi‐Bin Wei, Kai‐Yan Zhang, Xu‐Yang Feng, Hua Hu, Rong |
author_facet | Jiang, Yi‐Bin Wei, Kai‐Yan Zhang, Xu‐Yang Feng, Hua Hu, Rong |
author_sort | Jiang, Yi‐Bin |
collection | PubMed |
description | The predilection site of intracerebral hemorrhage (ICH) is in the basal ganglia, which is rich in white matter (WM) fiber bundles, such as cerebrospinal tract in the internal capsule. ICH induced damage to this area can easily lead to severe neurological dysfunction and affects the prognosis and quality of life of patients. At present, the pathophysiological mechanisms of white matter injury (WMI) after ICH have attracted researchers' attention, but studies on the repair and recovery mechanisms and therapy strategies remain rare. In this review, we mainly summarized the WM recovery and treatment strategies after ICH by updating the WMI‐related content by reviewing the latest researches and proposing the bottleneck of the current research. |
format | Online Article Text |
id | pubmed-6823871 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-68238712019-11-07 White matter repair and treatment strategy after intracerebral hemorrhage Jiang, Yi‐Bin Wei, Kai‐Yan Zhang, Xu‐Yang Feng, Hua Hu, Rong CNS Neurosci Ther Review Articles The predilection site of intracerebral hemorrhage (ICH) is in the basal ganglia, which is rich in white matter (WM) fiber bundles, such as cerebrospinal tract in the internal capsule. ICH induced damage to this area can easily lead to severe neurological dysfunction and affects the prognosis and quality of life of patients. At present, the pathophysiological mechanisms of white matter injury (WMI) after ICH have attracted researchers' attention, but studies on the repair and recovery mechanisms and therapy strategies remain rare. In this review, we mainly summarized the WM recovery and treatment strategies after ICH by updating the WMI‐related content by reviewing the latest researches and proposing the bottleneck of the current research. John Wiley and Sons Inc. 2019-10-02 /pmc/articles/PMC6823871/ /pubmed/31578825 http://dx.doi.org/10.1111/cns.13226 Text en © 2019 The Authors. CNS Neuroscience & Therapeutics Published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Articles Jiang, Yi‐Bin Wei, Kai‐Yan Zhang, Xu‐Yang Feng, Hua Hu, Rong White matter repair and treatment strategy after intracerebral hemorrhage |
title | White matter repair and treatment strategy after intracerebral hemorrhage |
title_full | White matter repair and treatment strategy after intracerebral hemorrhage |
title_fullStr | White matter repair and treatment strategy after intracerebral hemorrhage |
title_full_unstemmed | White matter repair and treatment strategy after intracerebral hemorrhage |
title_short | White matter repair and treatment strategy after intracerebral hemorrhage |
title_sort | white matter repair and treatment strategy after intracerebral hemorrhage |
topic | Review Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823871/ https://www.ncbi.nlm.nih.gov/pubmed/31578825 http://dx.doi.org/10.1111/cns.13226 |
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