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White matter repair and treatment strategy after intracerebral hemorrhage

The predilection site of intracerebral hemorrhage (ICH) is in the basal ganglia, which is rich in white matter (WM) fiber bundles, such as cerebrospinal tract in the internal capsule. ICH induced damage to this area can easily lead to severe neurological dysfunction and affects the prognosis and qua...

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Autores principales: Jiang, Yi‐Bin, Wei, Kai‐Yan, Zhang, Xu‐Yang, Feng, Hua, Hu, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823871/
https://www.ncbi.nlm.nih.gov/pubmed/31578825
http://dx.doi.org/10.1111/cns.13226
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author Jiang, Yi‐Bin
Wei, Kai‐Yan
Zhang, Xu‐Yang
Feng, Hua
Hu, Rong
author_facet Jiang, Yi‐Bin
Wei, Kai‐Yan
Zhang, Xu‐Yang
Feng, Hua
Hu, Rong
author_sort Jiang, Yi‐Bin
collection PubMed
description The predilection site of intracerebral hemorrhage (ICH) is in the basal ganglia, which is rich in white matter (WM) fiber bundles, such as cerebrospinal tract in the internal capsule. ICH induced damage to this area can easily lead to severe neurological dysfunction and affects the prognosis and quality of life of patients. At present, the pathophysiological mechanisms of white matter injury (WMI) after ICH have attracted researchers' attention, but studies on the repair and recovery mechanisms and therapy strategies remain rare. In this review, we mainly summarized the WM recovery and treatment strategies after ICH by updating the WMI‐related content by reviewing the latest researches and proposing the bottleneck of the current research.
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spelling pubmed-68238712019-11-07 White matter repair and treatment strategy after intracerebral hemorrhage Jiang, Yi‐Bin Wei, Kai‐Yan Zhang, Xu‐Yang Feng, Hua Hu, Rong CNS Neurosci Ther Review Articles The predilection site of intracerebral hemorrhage (ICH) is in the basal ganglia, which is rich in white matter (WM) fiber bundles, such as cerebrospinal tract in the internal capsule. ICH induced damage to this area can easily lead to severe neurological dysfunction and affects the prognosis and quality of life of patients. At present, the pathophysiological mechanisms of white matter injury (WMI) after ICH have attracted researchers' attention, but studies on the repair and recovery mechanisms and therapy strategies remain rare. In this review, we mainly summarized the WM recovery and treatment strategies after ICH by updating the WMI‐related content by reviewing the latest researches and proposing the bottleneck of the current research. John Wiley and Sons Inc. 2019-10-02 /pmc/articles/PMC6823871/ /pubmed/31578825 http://dx.doi.org/10.1111/cns.13226 Text en © 2019 The Authors. CNS Neuroscience & Therapeutics Published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Articles
Jiang, Yi‐Bin
Wei, Kai‐Yan
Zhang, Xu‐Yang
Feng, Hua
Hu, Rong
White matter repair and treatment strategy after intracerebral hemorrhage
title White matter repair and treatment strategy after intracerebral hemorrhage
title_full White matter repair and treatment strategy after intracerebral hemorrhage
title_fullStr White matter repair and treatment strategy after intracerebral hemorrhage
title_full_unstemmed White matter repair and treatment strategy after intracerebral hemorrhage
title_short White matter repair and treatment strategy after intracerebral hemorrhage
title_sort white matter repair and treatment strategy after intracerebral hemorrhage
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823871/
https://www.ncbi.nlm.nih.gov/pubmed/31578825
http://dx.doi.org/10.1111/cns.13226
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