Coagulation FXIII-A Protein Expression Defines Three Novel Sub-populations in Pediatric B-Cell Progenitor Acute Lymphoblastic Leukemia Characterized by Distinct Gene Expression Signatures

Background: Leukemic B-cell precursor (BCP) lymphoblasts were identified as a novel expression site for coagulation factor XIII subunit A (FXIII-A). Flow cytometry (FC) revealed three distinct expression patterns, i.e., FXIII-A negative, FXIII-A dim, and FXIII-A bright subgroups. The FXIII-A negativ...

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Detalles Bibliográficos
Autores principales: Gyurina, Katalin, Kárai, Bettina, Ujfalusi, Anikó, Hevessy, Zsuzsanna, Barna, Gábor, Jáksó, Pál, Pálfi-Mészáros, Gyöngyi, Póliska, Szilárd, Scholtz, Beáta, Kappelmayer, János, Zahuczky, Gábor, Kiss, Csongor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823876/
https://www.ncbi.nlm.nih.gov/pubmed/31709175
http://dx.doi.org/10.3389/fonc.2019.01063

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