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Systemic high-dose intravenous methotrexate in patients with central nervous system metastatic breast cancer

BACKGROUND: Infusion of high-dose intravenous methotrexate (MTX) has been demonstrating to penetrate the blood-brain barrier. The aim of this present study was to assess the efficacy and safety of high dose MTX in patients with central nervous system (CNS) metastases of breast cancer. METHODS: Twent...

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Detalles Bibliográficos
Autores principales:	Bazan, F., Dobi, E., Royer, B., Curtit, E., Mansi, L., Menneveau, N., Paillard, M. J., Meynard, G., Villanueva, C., Pivot, X., Chaigneau, L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823971/ https://www.ncbi.nlm.nih.gov/pubmed/31675937 http://dx.doi.org/10.1186/s12885-019-6228-6

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