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GLIPR1L1 is an IZUMO-binding protein required for optimal fertilization in the mouse

BACKGROUND: The sperm protein IZUMO1 (Izumo sperm-egg fusion 1) and its recently identified binding partner on the oolemma, IZUMO1R, are among the first ligand-receptor pairs shown to be essential for gamete recognition and adhesion. However, the IZUMO1-IZUMO1R interaction does not appear to be dire...

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Detalles Bibliográficos
Autores principales: Gaikwad, Avinash S., Anderson, Amanda L., Merriner, D. Jo, O’Connor, Anne E., Houston, Brendan J., Aitken, R. John, O’Bryan, Moira K., Nixon, Brett
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824042/
https://www.ncbi.nlm.nih.gov/pubmed/31672133
http://dx.doi.org/10.1186/s12915-019-0701-1