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Acetaminophen Intoxication Rapidly Induces Apoptosis of Intestinal Crypt Stem Cells and Enhances Intestinal Permeability

Acetaminophen (APAP)‐induced liver injury is the most common cause of acute liver failure (ALF) in the Western world. APAP toxicity progresses to multiorgan dysfunction and thus has broader whole‐body implications. Importantly, greater 30‐day mortality has been observed in liver transplant recipient...

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Detalles Bibliográficos
Autores principales: Chopyk, Daniel M., Stuart, Johnasha D., Zimmerman, Matthew G., Wen, Jing, Gumber, Sanjeev, Suthar, Mehul S., Thapa, Manoj, Czaja, Mark J., Grakoui, Arash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824060/
https://www.ncbi.nlm.nih.gov/pubmed/31701068
http://dx.doi.org/10.1002/hep4.1406