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Acetaminophen Intoxication Rapidly Induces Apoptosis of Intestinal Crypt Stem Cells and Enhances Intestinal Permeability
Acetaminophen (APAP)‐induced liver injury is the most common cause of acute liver failure (ALF) in the Western world. APAP toxicity progresses to multiorgan dysfunction and thus has broader whole‐body implications. Importantly, greater 30‐day mortality has been observed in liver transplant recipient...
Autores principales: | Chopyk, Daniel M., Stuart, Johnasha D., Zimmerman, Matthew G., Wen, Jing, Gumber, Sanjeev, Suthar, Mehul S., Thapa, Manoj, Czaja, Mark J., Grakoui, Arash |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824060/ https://www.ncbi.nlm.nih.gov/pubmed/31701068 http://dx.doi.org/10.1002/hep4.1406 |
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