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R‐spondin 2 Drives Liver Tumor Development in a Yes‐Associated Protein‐Dependent Manner

Each year, more than 25,000 people succumb to liver cancer in the United States, and this neoplasm represents the second cause of cancer‐related death globally. R‐spondins (RSPOs) are secreted regulators of Wnt signaling that function in development and promote tissue stem cell renewal. In cancer, R...

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Detalles Bibliográficos
Autores principales: Conboy, Caitlin B., Vélez‐Reyes, Germán L., Tschida, Barbara R., Hu, Hsiangyu, Kaufmann, Gabriel, Koes, Nicholas, Keller, Bryant, Alsinet, Clara, Cornellà, Helena, Pinyol, Roser, Abrahante, Juan E., Temiz, Nuri A., Linden, Michael A., Amin, Khalid, Kuka, Timothy P., Keng, Vincent W., Llovet, Josep M., Starr, Timothy K., Largaespada, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824083/
https://www.ncbi.nlm.nih.gov/pubmed/31701073
http://dx.doi.org/10.1002/hep4.1422