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The Effects of Dimethyl Fumarate on Atherosclerosis in the Apolipoprotein E-Deficient Mouse Model with Streptozotocin-Induced Hyperglycemia Mediated By the Nuclear Factor Erythroid 2-Related Factor 2/Antioxidant Response Element (Nrf2/ARE) Signaling Pathway

BACKGROUND: This study aimed to investigate the effects of dimethyl fumarate (DMF) on thoracic aortic atherosclerosis in the apolipoprotein E (apo-E)-deficient mouse model with streptozotocin (STZ)-induced hyperglycemia, and the signaling pathways involved. MATERIAL/METHODS: Eight-week-old ApoE−/− m...

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Detalles Bibliográficos
Autores principales: Luo, Man, Sun, Qingsong, Zhao, Hongmei, Tao, Jiali, Yan, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824188/
https://www.ncbi.nlm.nih.gov/pubmed/31645538
http://dx.doi.org/10.12659/MSM.918951

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