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A role for placental kisspeptin in β cell adaptation to pregnancy

During pregnancy the maternal pancreatic islets of Langerhans undergo adaptive changes to compensate for gestational insulin resistance. Kisspeptin has been shown to stimulate insulin release, through its receptor, GPR54. The placenta releases high levels of kisspeptin into the maternal circulation,...

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Detalles Bibliográficos
Autores principales: Bowe, James E., Hill, Thomas G., Hunt, Katharine F., Smith, Lorna I.F., Simpson, Sian J.S., Amiel, Stephanie A., Jones, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824306/
https://www.ncbi.nlm.nih.gov/pubmed/31619585
http://dx.doi.org/10.1172/jci.insight.124540

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