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A role for placental kisspeptin in β cell adaptation to pregnancy
During pregnancy the maternal pancreatic islets of Langerhans undergo adaptive changes to compensate for gestational insulin resistance. Kisspeptin has been shown to stimulate insulin release, through its receptor, GPR54. The placenta releases high levels of kisspeptin into the maternal circulation,...
Autores principales: | Bowe, James E., Hill, Thomas G., Hunt, Katharine F., Smith, Lorna I.F., Simpson, Sian J.S., Amiel, Stephanie A., Jones, Peter M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824306/ https://www.ncbi.nlm.nih.gov/pubmed/31619585 http://dx.doi.org/10.1172/jci.insight.124540 |
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