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Reward-Related Behavioral, Neurochemical and Electrophysiological Changes in a Rat Model of Autism Based on Prenatal Exposure to Valproic Acid

Prenatal exposure to the antiepileptic drug valproic acid (VPA) induces autism spectrum disorder (ASD) in humans and autistic-like behaviors in rodents, which makes it a good model to study the neural underpinnings of ASD. Rats prenatally exposed to VPA show profound deficits in the social domain. T...

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Detalles Bibliográficos
Autores principales: Schiavi, Sara, Iezzi, Daniela, Manduca, Antonia, Leone, Stefano, Melancia, Francesca, Carbone, Carmen, Petrella, Michele, Mannaioni, Guido, Masi, Alessio, Trezza, Viviana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824319/
https://www.ncbi.nlm.nih.gov/pubmed/31708750
http://dx.doi.org/10.3389/fncel.2019.00479