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Reward-Related Behavioral, Neurochemical and Electrophysiological Changes in a Rat Model of Autism Based on Prenatal Exposure to Valproic Acid
Prenatal exposure to the antiepileptic drug valproic acid (VPA) induces autism spectrum disorder (ASD) in humans and autistic-like behaviors in rodents, which makes it a good model to study the neural underpinnings of ASD. Rats prenatally exposed to VPA show profound deficits in the social domain. T...
Autores principales: | Schiavi, Sara, Iezzi, Daniela, Manduca, Antonia, Leone, Stefano, Melancia, Francesca, Carbone, Carmen, Petrella, Michele, Mannaioni, Guido, Masi, Alessio, Trezza, Viviana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824319/ https://www.ncbi.nlm.nih.gov/pubmed/31708750 http://dx.doi.org/10.3389/fncel.2019.00479 |
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