Hippo pathway deletion in adult resting cardiac fibroblasts initiates a cell state transition with spontaneous and self-sustaining fibrosis

Cardiac fibroblasts (CFs) respond to injury by transitioning through multiple cell states, including resting CFs, activated CFs, and myofibroblasts. We report here that Hippo signaling cell-autonomously regulates CF fate transitions and proliferation, and non-cell-autonomously regulates both myeloid...

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Detalles Bibliográficos
Autores principales: Xiao, Yang, Hill, Matthew C., Li, Lele, Deshmukh, Vaibhav, Martin, Thomas J., Wang, Jun, Martin, James F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824468/
https://www.ncbi.nlm.nih.gov/pubmed/31558567
http://dx.doi.org/10.1101/gad.329763.119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824468/
https://www.ncbi.nlm.nih.gov/pubmed/31558567
http://dx.doi.org/10.1101/gad.329763.119

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