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Novel COX-2 products of n-3 polyunsaturated fatty acid-ethanolamine-conjugates identified in RAW264.7 macrophages

Cyclooxygenase 2 (COX-2) plays a key role in the regulation of inflammation by catalyzing the oxygenation of PUFAs to prostaglandins (PGs) and hydroperoxides. Next to this, COX-2 can metabolize neutral lipids, including endocannabinoid-like esters and amides. We developed an LC-HRMS-based human reco...

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Detalles Bibliográficos
Autores principales:	de Bus, Ian, Zuilhof, Han, Witkamp, Renger, Balvers, Michiel, Albada, Bauke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Biochemistry and Molecular Biology 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824491/ https://www.ncbi.nlm.nih.gov/pubmed/31455615 http://dx.doi.org/10.1194/jlr.M094235

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