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Characterization of novel primary miRNA transcription units in human cells using Bru-seq nascent RNA sequencing

MicroRNAs (miRNAs) are key contributors to gene regulatory networks. Because miRNAs are processed from RNA polymerase II transcripts, insight into miRNA regulation requires a comprehensive understanding of the regulation of primary miRNA transcripts. We used Bru-seq nascent RNA sequencing and hidden...

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Detalles Bibliográficos
Autores principales: Bedi, Karan, Paulsen, Michelle T, Wilson, Thomas E, Ljungman, Mats
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824518/
https://www.ncbi.nlm.nih.gov/pubmed/31709421
http://dx.doi.org/10.1093/nargab/lqz014

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