Ang-(1-7)/ MAS1 receptor axis inhibits allergic airway inflammation via blockade of Src-mediated EGFR transactivation in a murine model of asthma

The angiotensin-(1–7) [Ang-(1–7)]/MAS1 receptor signaling axis is a key endogenous anti-inflammatory signaling pathway. However, the mechanisms by which its mediates the anti-inflammatory effects are not completely understood. Using an allergic murine model of asthma, we investigated whether Ang-1(1...

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Detalles Bibliográficos
Autores principales: El-Hashim, Ahmed Z., Khajah, Maitham A., Babyson, Rhema S., Renno, Waleed M., Ezeamuzie, Charles I., Benter, Ibrahim F., Akhtar, Saghir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824568/
https://www.ncbi.nlm.nih.gov/pubmed/31675376
http://dx.doi.org/10.1371/journal.pone.0224163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824568/
https://www.ncbi.nlm.nih.gov/pubmed/31675376
http://dx.doi.org/10.1371/journal.pone.0224163

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