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Effect of local anesthesia with lidocaine on perioperative proinflammatory cytokine levels in plasma and cerebrospinal fluid in cerebral aneurysm patients: Study protocol for a randomized clinical trial

BACKGROUND: Cerebral aneurysm surgery has significant mortality and morbidity rate. Inflammation plays a key role in the pathogenesis of intracranial aneurysms, their rupture, subarachnoid hemorrhage and neurologic complications. Proinflammatory cytokine level in blood and cerebrospinal fluid (CSF)...

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Detalles Bibliográficos
Autores principales: Matas, Marijana, Sotošek, Vlatka, Kozmar, Ana, Likić, Robert, Sekulić, Ante
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824720/
https://www.ncbi.nlm.nih.gov/pubmed/31626100
http://dx.doi.org/10.1097/MD.0000000000017450