Idiopathic pulmonary arterial hypertension associated with a novel frameshift mutation in the bone morphogenetic protein receptor II gene and enhanced bone morphogenetic protein signaling: A case report

RATIONALE: Idiopathic pulmonary arterial hypertension (IPAH) is characterized by intense remodeling of small pulmonary arteries. Loss-of-function mutation of bone morphogenetic protein receptor II (BMPR2) gene and exaggerated activation of transforming growth factor (TGF)-β signaling play a critical...

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Detalles Bibliográficos
Autores principales: Choi, Sun Ha, Jung, Youn-Kwan, Jang, Ji-Ae, Han, Seungwoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
6700
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824762/
https://www.ncbi.nlm.nih.gov/pubmed/31626133
http://dx.doi.org/10.1097/MD.0000000000017594

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