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The role of ligand-gated conformational changes in enzyme catalysis
Structural and biochemical studies on diverse enzymes have highlighted the importance of ligand-gated conformational changes in enzyme catalysis, where the intrinsic binding energy of the common phosphoryl group of their substrates is used to drive energetically unfavorable conformational changes in...
Autores principales: | Moreira, Cátia, Calixto, Ana Rita, Richard, John P., Kamerlin, Shina Caroline Lynn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824834/ https://www.ncbi.nlm.nih.gov/pubmed/31657438 http://dx.doi.org/10.1042/BST20190298 |
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