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The mechanosensitive ion channel TRAAK is localized to the mammalian node of Ranvier

TRAAK is a membrane tension-activated K(+) channel that has been associated through behavioral studies to mechanical nociception. We used specific monoclonal antibodies in mice to show that TRAAK is localized exclusively to nodes of Ranvier, the action potential propagating elements of myelinated ne...

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Detalles Bibliográficos
Autores principales:	Brohawn, Stephen G, Wang, Weiwei, Handler, Annie, Campbell, Ernest B, Schwarz, Jürgen R, MacKinnon, Roderick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824864/ https://www.ncbi.nlm.nih.gov/pubmed/31674909 http://dx.doi.org/10.7554/eLife.50403

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