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Glutaminolysis‐related genes determine sensitivity to xCT‐targeted therapy in head and neck squamous cell carcinoma
Targeting the function of membrane transporters in cancer stemlike cells is a potential new therapeutic approach. Cystine‐glutamate antiporter xCT expressed in CD44 variant (CD44v)‐expressing cancer cells contributes to the resistance to oxidative stress as well as cancer therapy through promoting g...
Autores principales: | Okazaki, Shogo, Umene, Kiyoko, Yamasaki, Juntaro, Suina, Kentaro, Otsuki, Yuji, Yoshikawa, Momoko, Minami, Yushi, Masuko, Takashi, Kawaguchi, Sho, Nakayama, Hideki, Banno, Kouji, Aoki, Daisuke, Saya, Hideyuki, Nagano, Osamu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825010/ https://www.ncbi.nlm.nih.gov/pubmed/31444923 http://dx.doi.org/10.1111/cas.14182 |
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