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G9a and histone deacetylases are crucial for Snail2‐mediated E‐cadherin repression and metastasis in hepatocellular carcinoma

Functional E‐cadherin loss, a hallmark of epithelial‐mesenchymal transition (EMT), is important for metastasis. However, the mechanism of Snail2 in hepatocellular carcinoma (HCC) EMT and metastasis remains unclear. Here, we showed that Snail2 was upregulated in primary HCC, and significantly increas...

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Detalles Bibliográficos
Autores principales: Hu, Yue, Zheng, Yayuan, Dai, Mingrui, Wang, Xueju, Wu, Jiaxin, Yu, Bin, Zhang, Haihong, Cui, Yinqiu, Kong, Wei, Wu, Hui, Yu, Xianghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825017/
https://www.ncbi.nlm.nih.gov/pubmed/31432592
http://dx.doi.org/10.1111/cas.14173