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Factors Influencing the Safety and Efficiency of Antifungal Prophylaxis with Posaconazole in Children with Hematological Diseases: From Genetics to Polypharmacotherapy

The aim of this study was to determine the impact of ABCB1 polymorphism, BMI, age and drug co-administration on safety and efficiency of posaconazole (PCZ) oral suspension treatment in children with hematological diseases. Seventy children were included in the study. ABCB1 polymorphism in fifty-eigh...

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Detalles Bibliográficos
Autores principales: Sienkiewicz-Oleszkiewicz, Beata, Urbańczyk, Kamila, Stachowiak, Mateusz, Rodziewicz, Anna, Zięba, Aleksander, Kałwak, Krzysztof, Wiela-Hojeńska, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer India 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825114/
https://www.ncbi.nlm.nih.gov/pubmed/31741622
http://dx.doi.org/10.1007/s12288-019-01134-5