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Synergized regulation of NK cell education by NKG2A and specific Ly49 family members

Mice lacking MHC class-I (MHC-I) display severe defects in natural killer (NK) cell functional maturation, a process designated as “education”. Whether self-MHC-I specific Ly49 family receptors and NKG2A, which are closely linked within the NK gene complex (NKC) locus, are essential for NK cell educ...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoqian, Feng, Jin, Chen, Shasha, Yang, Haoyan, Dong, Zhongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825122/
https://www.ncbi.nlm.nih.gov/pubmed/31676749
http://dx.doi.org/10.1038/s41467-019-13032-5

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