The transcription factor ERG regulates a low shear stress-induced anti-thrombotic pathway in the microvasculature

Endothelial cells actively maintain an anti-thrombotic environment; loss of this protective function may lead to thrombosis and systemic coagulopathy. The transcription factor ERG is essential to maintain endothelial homeostasis. Here, we show that inducible endothelial ERG deletion (Erg(iEC-KO)) in...

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Detalles Bibliográficos
Autores principales: Peghaire, C., Dufton, N. P., Lang, M., Salles-Crawley, I. I., Ahnström, J., Kalna, V., Raimondi, C., Pericleous, C., Inuabasi, L., Kiseleva, R., Muzykantov, V. R., Mason, J. C., Birdsey, G. M., Randi, A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825134/
https://www.ncbi.nlm.nih.gov/pubmed/31676784
http://dx.doi.org/10.1038/s41467-019-12897-w

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