Cargando…

Infant airway microbiota and topical immune perturbations in the origins of childhood asthma

Asthma is believed to arise through early life aberrant immune development in response to environmental exposures that may influence the airway microbiota. Here, we examine the airway microbiota during the first three months of life by 16S rRNA gene amplicon sequencing in the population-based Copenh...

Descripción completa

Detalles Bibliográficos
Autores principales:	Thorsen, Jonathan, Rasmussen, Morten A., Waage, Johannes, Mortensen, Martin, Brejnrod, Asker, Bønnelykke, Klaus, Chawes, Bo L., Brix, Susanne, Sørensen, Søren J., Stokholm, Jakob, Bisgaard, Hans
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825176/ https://www.ncbi.nlm.nih.gov/pubmed/31676759 http://dx.doi.org/10.1038/s41467-019-12989-7

Ejemplares similares

Prenatal dietary supplements influence the infant airway microbiota in a randomized factorial clinical trial
por: Hjelmsø, Mathis H., et al.
Publicado: (2020)

Large-scale benchmarking reveals false discoveries and count transformation sensitivity in 16S rRNA gene amplicon data analysis methods used in microbiome studies
por: Thorsen, Jonathan, et al.
Publicado: (2016)

Maturation of the gut microbiome and risk of asthma in childhood
por: Stokholm, Jakob, et al.
Publicado: (2018)

Publisher Correction: Maturation of the gut microbiome and risk of asthma in childhood
por: Stokholm, Jakob, et al.
Publicado: (2018)

Levels of Systemic Low-grade Inflammation in Pregnant Mothers and Their Offspring are Correlated
por: Fink, Nadia Rahman, et al.
Publicado: (2019)

Short- and long-term impacts of azithromycin treatment on the gut microbiota in children: A double-blind, randomized, placebo-controlled trial
por: Wei, Shaodong, et al.
Publicado: (2018)

Modeling transfer of vaginal microbiota from mother to infant in early life
por: Mortensen, Martin Steen, et al.
Publicado: (2021)

Airway obstruction and bronchial reactivity from age 1 month until 13 years in children with asthma: A prospective birth cohort study
por: Hallas, Henrik Wegener, et al.
Publicado: (2019)

The developing hypopharyngeal microbiota in early life
por: Mortensen, Martin Steen, et al.
Publicado: (2016)

Neonates with reduced neonatal lung function have systemic low-grade inflammation
por: Chawes, Bo L.K., et al.
Publicado: (2015)

Neonatal Urine Metabolic Profiling and Development of Childhood Asthma
por: Chawes, Bo L., et al.
Publicado: (2019)

The developing airway and gut microbiota in early life is influenced by age of older siblings
por: Christensen, Emil Dalgaard, et al.
Publicado: (2022)

The airway microbiota of neonates colonized with asthma-associated pathogenic bacteria
por: Thorsen, Jonathan, et al.
Publicado: (2023)

Fish-oil supplementation in pregnancy, child metabolomics and asthma risk
por: Rago, Daniela, et al.
Publicado: (2019)

Handgrip strength associates with effort-dependent lung function measures among adolescents with and without asthma
por: Hesselberg, Laura Marie, et al.
Publicado: (2023)

Prenatal vitamin D supplementation reduces risk of asthma/recurrent wheeze in early childhood: A combined analysis of two randomized controlled trials
por: Wolsk, Helene M., et al.
Publicado: (2017)

Reduced IL-2 response from peripheral blood mononuclear cells exposed to bacteria at 6 months of age is associated with elevated total-IgE and allergic rhinitis during the first 7 years of life
por: Wang, Ni, et al.
Publicado: (2019)

Limited clinical value of exhaled volatile organic compound measurements in childhood asthma
por: Fuglsbjerg, Maria G., et al.
Publicado: (2018)

Delayed Motor Milestones Achievement in Infancy Associates with Perturbations of Amino Acids and Lipid Metabolic Pathways
por: Vinding, Rebecca Kofod, et al.
Publicado: (2020)

Childhood asthma is associated with development of type 1 diabetes and inflammatory bowel diseases: a Danish nationwide registry study
por: Liljendahl, Mie Sylow, et al.
Publicado: (2022)

Safety of High-Dose Vitamin D Supplementation Among Children Aged 0 to 6 Years: A Systematic Review and Meta-analysis
por: Brustad, Nicklas, et al.
Publicado: (2022)

High-dose vitamin D supplementation in pregnancy and 25(OH)D sufficiency in childhood reduce the risk of fractures and improve bone mineralization in childhood: Follow-up of a randomized clinical trial
por: Brustad, Nicklas, et al.
Publicado: (2021)

Environmental shaping of the bacterial and fungal community in infant bed dust and correlations with the airway microbiota
por: Gupta, Shashank, et al.
Publicado: (2020)

Cost of Illness in Young Children: A Prospective Birth Cohort Study
por: Nørgaard, Sarah Kristine, et al.
Publicado: (2021)

Effect of fish oil supplementation in pregnancy on bone, lean, and fat mass at six years: randomised clinical trial
por: Vinding, Rebecca Kofod, et al.
Publicado: (2018)

Antibiotic exposure in infancy and development of BMI and body composition in childhood
por: Sejersen, Tobias Steen, et al.
Publicado: (2019)

Exposures to perfluoroalkyl substances and asthma phenotypes in childhood: an investigation of the COPSAC2010 cohort
por: Sevelsted, Astrid, et al.
Publicado: (2023)

Season of Birth Impacts the Neonatal Nasopharyngeal Microbiota
por: Schoos, Ann-Marie Malby, et al.
Publicado: (2020)

High-Dose Vitamin D Supplementation in Pregnancy and Neurodevelopment in Childhood: A Prespecified Secondary Analysis of a Randomized Clinical Trial
por: Sass, Laerke, et al.
Publicado: (2020)

Azithromycin and high-dose vitamin D for treatment and prevention of asthma-like episodes in hospitalised preschool children: study protocol for a combined double-blind randomised controlled trial
por: Kyvsgaard, Julie Nyholm, et al.
Publicado: (2022)

Environmental and Genetic Determinants of Serum 25(OH)-Vitamin D Levels during Pregnancy and Early Childhood
por: Schoos, Ann-Marie Malby, et al.
Publicado: (2019)

Associations of 25 Hydroxyvitamin D and High Sensitivity C-reactive Protein Levels in Early Life
por: Brustad, Nicklas, et al.
Publicado: (2021)

Ecological succession in the vaginal microbiota during pregnancy and birth
por: Rasmussen, M. A., et al.
Publicado: (2020)

Living with Cat and Dog Increases Vaginal Colonization with E. coli in Pregnant Women
por: Stokholm, Jakob, et al.
Publicado: (2012)

Legacy Effects on the Recovery of Soil Bacterial Communities from Extreme Temperature Perturbation
por: Jurburg, Stephanie D., et al.
Publicado: (2017)

Prevalence and Predictors of Antibiotic Administration during Pregnancy and Birth
por: Stokholm, Jakob, et al.
Publicado: (2013)

Cord Blood 25(OH)-Vitamin D Deficiency and Childhood Asthma, Allergy and Eczema: The COPSAC(2000) Birth Cohort Study
por: Chawes, Bo L., et al.
Publicado: (2014)

Amplicon sequencing provides more accurate microbiome information in healthy children compared to culturing
por: Gupta, Shashank, et al.
Publicado: (2019)

The microbiome of captive hamadryas baboons
por: Li, Xuanji, et al.
Publicado: (2020)

Azithromycin for episodes with asthma-like symptoms in young children aged 1–3 years: a randomised, double-blind, placebo-controlled trial
por: Stokholm, Jakob, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_tmd2r2721kf3pb6eauvpvkmjsv