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Integrated solid-state NMR and molecular dynamics modeling determines membrane insertion of human β-defensin analog
Human β-defensins (hBD) play central roles in antimicrobial activities against various microorganisms and in immune-regulation. These peptides perturb phospholipid membranes for function, but it is not well understood how defensins approach, insert and finally disrupt membranes on the molecular leve...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825183/ https://www.ncbi.nlm.nih.gov/pubmed/31701030 http://dx.doi.org/10.1038/s42003-019-0653-6 |