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Autophagy is inhibited by ubiquitin ligase activity in the nervous system
Autophagy is an intracellular catabolic process prominent in starvation, aging and disease. Neuronal autophagy is particularly important, as it affects the development and function of the nervous system, and is heavily implicated in neurodegenerative disease. Nonetheless, how autophagy is regulated...
Autores principales: | Crawley, Oliver, Opperman, Karla J., Desbois, Muriel, Adrados, Isabel, Borgen, Melissa A., Giles, Andrew C., Duckett, Derek R., Grill, Brock |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825199/ https://www.ncbi.nlm.nih.gov/pubmed/31676756 http://dx.doi.org/10.1038/s41467-019-12804-3 |
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