Cargando…

Cross-sectional study of patient-reported fatigue, physical activity and cardiovascular status in men after robotic-assisted radical prostatectomy

PURPOSE: Patient-reported fatigue after robotic-assisted radical prostatectomy (RARP) has not been characterised to date. Fatigue after other prostate cancer (PCa) treatments is known to impact on patient-reported quality of life. The aim of this study was to characterise fatigue, physical activity...

Descripción completa

Detalles Bibliográficos
Autores principales: Ashton, Ruth E., Tew, Garry A., Robson, Wendy A., Saxton, John M., Aning, Jonathan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825227/
https://www.ncbi.nlm.nih.gov/pubmed/30969369
http://dx.doi.org/10.1007/s00520-019-04794-1
_version_ 1783464866582888448
author Ashton, Ruth E.
Tew, Garry A.
Robson, Wendy A.
Saxton, John M.
Aning, Jonathan J.
author_facet Ashton, Ruth E.
Tew, Garry A.
Robson, Wendy A.
Saxton, John M.
Aning, Jonathan J.
author_sort Ashton, Ruth E.
collection PubMed
description PURPOSE: Patient-reported fatigue after robotic-assisted radical prostatectomy (RARP) has not been characterised to date. Fatigue after other prostate cancer (PCa) treatments is known to impact on patient-reported quality of life. The aim of this study was to characterise fatigue, physical activity levels and cardiovascular status post-RARP. METHODS: Between October 2016 and March 2017, men post-RARP or on androgen deprivation therapy (ADT) were invited into the study. Participants were asked to complete the Brief Fatigue Inventory (BFI) and Stage of Change and Scottish Physical Activity Questionnaires (SPAQ) over a 2-week period. Outcome measures were patient-reported fatigue, physical activity levels and the 10-year risk of cardiovascular disease (Q-Risk). Data were analysed in SPSS. RESULTS: 96/117 (82%) men approached consented to participate; of these, 62/96 (65%) returned complete questionnaire data (RARP n = 42, ADT n = 20). All men reported fatigue with 9/42 (21%) post-RARP reporting clinically significant fatigue. Physical activity did not correlate with fatigue. On average, both groups were overweight (BMI 27.0 ± 3.9 kg/m(2) and 27.8 ± 12.3 kg/m(2) for RARP and ADT, respectively) and the post-RARP group had an 18.1% ± 7.4% Q-Risk2 score. CONCLUSIONS: A proportion of men is at increased risk of cardiovascular disease within 10 years post-RARP and have substantial levels of fatigue; therefore, clinicians should consider including these factors when counselling patients about RARP. Additionally, men post-RARP did not meet the recommended guidelines for resistance-based exercise. Future research is needed to establish whether interventions including resistance-based exercise can improve health and fatigue levels in this population.
format Online
Article
Text
id pubmed-6825227
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Springer Berlin Heidelberg
record_format MEDLINE/PubMed
spelling pubmed-68252272019-11-06 Cross-sectional study of patient-reported fatigue, physical activity and cardiovascular status in men after robotic-assisted radical prostatectomy Ashton, Ruth E. Tew, Garry A. Robson, Wendy A. Saxton, John M. Aning, Jonathan J. Support Care Cancer Original Article PURPOSE: Patient-reported fatigue after robotic-assisted radical prostatectomy (RARP) has not been characterised to date. Fatigue after other prostate cancer (PCa) treatments is known to impact on patient-reported quality of life. The aim of this study was to characterise fatigue, physical activity levels and cardiovascular status post-RARP. METHODS: Between October 2016 and March 2017, men post-RARP or on androgen deprivation therapy (ADT) were invited into the study. Participants were asked to complete the Brief Fatigue Inventory (BFI) and Stage of Change and Scottish Physical Activity Questionnaires (SPAQ) over a 2-week period. Outcome measures were patient-reported fatigue, physical activity levels and the 10-year risk of cardiovascular disease (Q-Risk). Data were analysed in SPSS. RESULTS: 96/117 (82%) men approached consented to participate; of these, 62/96 (65%) returned complete questionnaire data (RARP n = 42, ADT n = 20). All men reported fatigue with 9/42 (21%) post-RARP reporting clinically significant fatigue. Physical activity did not correlate with fatigue. On average, both groups were overweight (BMI 27.0 ± 3.9 kg/m(2) and 27.8 ± 12.3 kg/m(2) for RARP and ADT, respectively) and the post-RARP group had an 18.1% ± 7.4% Q-Risk2 score. CONCLUSIONS: A proportion of men is at increased risk of cardiovascular disease within 10 years post-RARP and have substantial levels of fatigue; therefore, clinicians should consider including these factors when counselling patients about RARP. Additionally, men post-RARP did not meet the recommended guidelines for resistance-based exercise. Future research is needed to establish whether interventions including resistance-based exercise can improve health and fatigue levels in this population. Springer Berlin Heidelberg 2019-04-10 2019 /pmc/articles/PMC6825227/ /pubmed/30969369 http://dx.doi.org/10.1007/s00520-019-04794-1 Text en © The Author(s) 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Article
Ashton, Ruth E.
Tew, Garry A.
Robson, Wendy A.
Saxton, John M.
Aning, Jonathan J.
Cross-sectional study of patient-reported fatigue, physical activity and cardiovascular status in men after robotic-assisted radical prostatectomy
title Cross-sectional study of patient-reported fatigue, physical activity and cardiovascular status in men after robotic-assisted radical prostatectomy
title_full Cross-sectional study of patient-reported fatigue, physical activity and cardiovascular status in men after robotic-assisted radical prostatectomy
title_fullStr Cross-sectional study of patient-reported fatigue, physical activity and cardiovascular status in men after robotic-assisted radical prostatectomy
title_full_unstemmed Cross-sectional study of patient-reported fatigue, physical activity and cardiovascular status in men after robotic-assisted radical prostatectomy
title_short Cross-sectional study of patient-reported fatigue, physical activity and cardiovascular status in men after robotic-assisted radical prostatectomy
title_sort cross-sectional study of patient-reported fatigue, physical activity and cardiovascular status in men after robotic-assisted radical prostatectomy
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825227/
https://www.ncbi.nlm.nih.gov/pubmed/30969369
http://dx.doi.org/10.1007/s00520-019-04794-1
work_keys_str_mv AT ashtonruthe crosssectionalstudyofpatientreportedfatiguephysicalactivityandcardiovascularstatusinmenafterroboticassistedradicalprostatectomy
AT tewgarrya crosssectionalstudyofpatientreportedfatiguephysicalactivityandcardiovascularstatusinmenafterroboticassistedradicalprostatectomy
AT robsonwendya crosssectionalstudyofpatientreportedfatiguephysicalactivityandcardiovascularstatusinmenafterroboticassistedradicalprostatectomy
AT saxtonjohnm crosssectionalstudyofpatientreportedfatiguephysicalactivityandcardiovascularstatusinmenafterroboticassistedradicalprostatectomy
AT aningjonathanj crosssectionalstudyofpatientreportedfatiguephysicalactivityandcardiovascularstatusinmenafterroboticassistedradicalprostatectomy