Redirection of SKN-1 abates the negative metabolic outcomes of a perceived pathogen infection

Early host responses toward pathogens are essential for defense against infection. In Caenorhabditis elegans, the transcription factor, SKN-1, regulates cellular defenses during xenobiotic intoxication and bacterial infection. However, constitutive activation of SKN-1 results in pleiotropic outcomes...

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Detalles Bibliográficos
Autores principales: Nhan, James D., Turner, Christian D., Anderson, Sarah M., Yen, Chia-An, Dalton, Hans M., Cheesman, Hilary K., Ruter, Dana L., Uma Naresh, Nandhitha, Haynes, Cole M., Soukas, Alexander A., Pukkila-Worley, Read, Curran, Sean P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825279/
https://www.ncbi.nlm.nih.gov/pubmed/31611372
http://dx.doi.org/10.1073/pnas.1909666116

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