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The contribution of host cell-directed vs. parasite-directed immunity to the disease and dynamics of malaria infections

Hosts defend themselves against pathogens by mounting an immune response. Fully understanding the immune response as a driver of host disease and pathogen evolution requires a quantitative account of its impact on parasite population dynamics. Here, we use a data-driven modeling approach to quantify...

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Detalles Bibliográficos
Autores principales: Wale, Nina, Jones, Matthew J., Sim, Derek G., Read, Andrew F., King, Aaron A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825298/
https://www.ncbi.nlm.nih.gov/pubmed/31615885
http://dx.doi.org/10.1073/pnas.1908147116