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Relationship between comorbidities and treatment decision-making in elderly hip fracture patients
BACKGROUND: Elderly patients are at a higher risk for hip fracture. Moreover, hospitalized elderly patients with hip fracture are vulnerable to adverse outcomes including higher mortality rate and long-term disability. Treatment decision-making with respect to surgical procedure and perioperative ma...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825646/ https://www.ncbi.nlm.nih.gov/pubmed/30993661 http://dx.doi.org/10.1007/s40520-019-01134-5 |
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author | Wei, Jinxing Zeng, Li Li, Shitong Luo, Fang Xiang, Zhou Ding, Qunfang |
author_facet | Wei, Jinxing Zeng, Li Li, Shitong Luo, Fang Xiang, Zhou Ding, Qunfang |
author_sort | Wei, Jinxing |
collection | PubMed |
description | BACKGROUND: Elderly patients are at a higher risk for hip fracture. Moreover, hospitalized elderly patients with hip fracture are vulnerable to adverse outcomes including higher mortality rate and long-term disability. Treatment decision-making with respect to surgical procedure and perioperative management of these patients is typically challenging owing to the presence of multiple comorbid conditions. AIMS: The purpose of this study was to investigate the relationship between comorbidities in elderly patients with hip fracture and the treatment decision-making. METHODS: 884 geriatric patients (age ≥ 60 years) with hip fracture were included. Comorbidities related to age were measured using the Charlson Co-morbidity Index (CCI) and age-adjusted CCI. The CCI of each geriatric hip fracture patient was calculated based on data retrieved from the medical records. The relationship of CCI and age-adjusted CCI with surgical procedure, time-to-surgery, length of hospital stay, and perioperative management (transfusion, anti-coagulation, and analgesia) was assessed. RESULTS: Mean age of patients was 78.01 ± 8.62 years. The mean CCI was 0.79 ± 0.036; the mean age-adjusted CCI was 4.15 ± 0.047. The CCI was significantly associated with time-to-surgery (P = 0.004), surgical treatment (P < 0.001), and transfusion (P = 0.023). The age-adjusted CCI was significantly associated with surgical treatment (P < 0.001), analgesia (P = 0.003) and transfusion (P < 0.001). The length of hospital stay was associated with both CCI (P = 0.041), age-adjusted CCI (P = 0.002), and hypertension (P = 0.012). Hospital expenses showed a significant association with CCI (P = 0.000), age-adjusted CCI (P = 0.029), osteoprosis (P = 0.007), and hypertension (P = 0.001). CONCLUSION: In this study, comorbidities were positively associated with surgical procedure and perioperative management of elderly patients with hip fracture. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s40520-019-01134-5) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-6825646 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-68256462019-11-05 Relationship between comorbidities and treatment decision-making in elderly hip fracture patients Wei, Jinxing Zeng, Li Li, Shitong Luo, Fang Xiang, Zhou Ding, Qunfang Aging Clin Exp Res Original Article BACKGROUND: Elderly patients are at a higher risk for hip fracture. Moreover, hospitalized elderly patients with hip fracture are vulnerable to adverse outcomes including higher mortality rate and long-term disability. Treatment decision-making with respect to surgical procedure and perioperative management of these patients is typically challenging owing to the presence of multiple comorbid conditions. AIMS: The purpose of this study was to investigate the relationship between comorbidities in elderly patients with hip fracture and the treatment decision-making. METHODS: 884 geriatric patients (age ≥ 60 years) with hip fracture were included. Comorbidities related to age were measured using the Charlson Co-morbidity Index (CCI) and age-adjusted CCI. The CCI of each geriatric hip fracture patient was calculated based on data retrieved from the medical records. The relationship of CCI and age-adjusted CCI with surgical procedure, time-to-surgery, length of hospital stay, and perioperative management (transfusion, anti-coagulation, and analgesia) was assessed. RESULTS: Mean age of patients was 78.01 ± 8.62 years. The mean CCI was 0.79 ± 0.036; the mean age-adjusted CCI was 4.15 ± 0.047. The CCI was significantly associated with time-to-surgery (P = 0.004), surgical treatment (P < 0.001), and transfusion (P = 0.023). The age-adjusted CCI was significantly associated with surgical treatment (P < 0.001), analgesia (P = 0.003) and transfusion (P < 0.001). The length of hospital stay was associated with both CCI (P = 0.041), age-adjusted CCI (P = 0.002), and hypertension (P = 0.012). Hospital expenses showed a significant association with CCI (P = 0.000), age-adjusted CCI (P = 0.029), osteoprosis (P = 0.007), and hypertension (P = 0.001). CONCLUSION: In this study, comorbidities were positively associated with surgical procedure and perioperative management of elderly patients with hip fracture. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s40520-019-01134-5) contains supplementary material, which is available to authorized users. Springer International Publishing 2019-04-16 2019 /pmc/articles/PMC6825646/ /pubmed/30993661 http://dx.doi.org/10.1007/s40520-019-01134-5 Text en © The Author(s) 2019 OpenAccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Original Article Wei, Jinxing Zeng, Li Li, Shitong Luo, Fang Xiang, Zhou Ding, Qunfang Relationship between comorbidities and treatment decision-making in elderly hip fracture patients |
title | Relationship between comorbidities and treatment decision-making in elderly hip fracture patients |
title_full | Relationship between comorbidities and treatment decision-making in elderly hip fracture patients |
title_fullStr | Relationship between comorbidities and treatment decision-making in elderly hip fracture patients |
title_full_unstemmed | Relationship between comorbidities and treatment decision-making in elderly hip fracture patients |
title_short | Relationship between comorbidities and treatment decision-making in elderly hip fracture patients |
title_sort | relationship between comorbidities and treatment decision-making in elderly hip fracture patients |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825646/ https://www.ncbi.nlm.nih.gov/pubmed/30993661 http://dx.doi.org/10.1007/s40520-019-01134-5 |
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