Cargando…

Relationship between comorbidities and treatment decision-making in elderly hip fracture patients

BACKGROUND: Elderly patients are at a higher risk for hip fracture. Moreover, hospitalized elderly patients with hip fracture are vulnerable to adverse outcomes including higher mortality rate and long-term disability. Treatment decision-making with respect to surgical procedure and perioperative ma...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Jinxing, Zeng, Li, Li, Shitong, Luo, Fang, Xiang, Zhou, Ding, Qunfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825646/
https://www.ncbi.nlm.nih.gov/pubmed/30993661
http://dx.doi.org/10.1007/s40520-019-01134-5
_version_ 1783464923734474752
author Wei, Jinxing
Zeng, Li
Li, Shitong
Luo, Fang
Xiang, Zhou
Ding, Qunfang
author_facet Wei, Jinxing
Zeng, Li
Li, Shitong
Luo, Fang
Xiang, Zhou
Ding, Qunfang
author_sort Wei, Jinxing
collection PubMed
description BACKGROUND: Elderly patients are at a higher risk for hip fracture. Moreover, hospitalized elderly patients with hip fracture are vulnerable to adverse outcomes including higher mortality rate and long-term disability. Treatment decision-making with respect to surgical procedure and perioperative management of these patients is typically challenging owing to the presence of multiple comorbid conditions. AIMS: The purpose of this study was to investigate the relationship between comorbidities in elderly patients with hip fracture and the treatment decision-making. METHODS: 884 geriatric patients (age ≥ 60 years) with hip fracture were included. Comorbidities related to age were measured using the Charlson Co-morbidity Index (CCI) and age-adjusted CCI. The CCI of each geriatric hip fracture patient was calculated based on data retrieved from the medical records. The relationship of CCI and age-adjusted CCI with surgical procedure, time-to-surgery, length of hospital stay, and perioperative management (transfusion, anti-coagulation, and analgesia) was assessed. RESULTS: Mean age of patients was 78.01 ± 8.62 years. The mean CCI was 0.79 ± 0.036; the mean age-adjusted CCI was 4.15 ± 0.047. The CCI was significantly associated with time-to-surgery (P = 0.004), surgical treatment (P < 0.001), and transfusion (P = 0.023). The age-adjusted CCI was significantly associated with surgical treatment (P < 0.001), analgesia (P = 0.003) and transfusion (P < 0.001). The length of hospital stay was associated with both CCI (P = 0.041), age-adjusted CCI (P = 0.002), and hypertension (P = 0.012). Hospital expenses showed a significant association with CCI (P = 0.000), age-adjusted CCI (P = 0.029), osteoprosis (P = 0.007), and hypertension (P = 0.001). CONCLUSION: In this study, comorbidities were positively associated with surgical procedure and perioperative management of elderly patients with hip fracture. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s40520-019-01134-5) contains supplementary material, which is available to authorized users.
format Online
Article
Text
id pubmed-6825646
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Springer International Publishing
record_format MEDLINE/PubMed
spelling pubmed-68256462019-11-05 Relationship between comorbidities and treatment decision-making in elderly hip fracture patients Wei, Jinxing Zeng, Li Li, Shitong Luo, Fang Xiang, Zhou Ding, Qunfang Aging Clin Exp Res Original Article BACKGROUND: Elderly patients are at a higher risk for hip fracture. Moreover, hospitalized elderly patients with hip fracture are vulnerable to adverse outcomes including higher mortality rate and long-term disability. Treatment decision-making with respect to surgical procedure and perioperative management of these patients is typically challenging owing to the presence of multiple comorbid conditions. AIMS: The purpose of this study was to investigate the relationship between comorbidities in elderly patients with hip fracture and the treatment decision-making. METHODS: 884 geriatric patients (age ≥ 60 years) with hip fracture were included. Comorbidities related to age were measured using the Charlson Co-morbidity Index (CCI) and age-adjusted CCI. The CCI of each geriatric hip fracture patient was calculated based on data retrieved from the medical records. The relationship of CCI and age-adjusted CCI with surgical procedure, time-to-surgery, length of hospital stay, and perioperative management (transfusion, anti-coagulation, and analgesia) was assessed. RESULTS: Mean age of patients was 78.01 ± 8.62 years. The mean CCI was 0.79 ± 0.036; the mean age-adjusted CCI was 4.15 ± 0.047. The CCI was significantly associated with time-to-surgery (P = 0.004), surgical treatment (P < 0.001), and transfusion (P = 0.023). The age-adjusted CCI was significantly associated with surgical treatment (P < 0.001), analgesia (P = 0.003) and transfusion (P < 0.001). The length of hospital stay was associated with both CCI (P = 0.041), age-adjusted CCI (P = 0.002), and hypertension (P = 0.012). Hospital expenses showed a significant association with CCI (P = 0.000), age-adjusted CCI (P = 0.029), osteoprosis (P = 0.007), and hypertension (P = 0.001). CONCLUSION: In this study, comorbidities were positively associated with surgical procedure and perioperative management of elderly patients with hip fracture. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s40520-019-01134-5) contains supplementary material, which is available to authorized users. Springer International Publishing 2019-04-16 2019 /pmc/articles/PMC6825646/ /pubmed/30993661 http://dx.doi.org/10.1007/s40520-019-01134-5 Text en © The Author(s) 2019 OpenAccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Article
Wei, Jinxing
Zeng, Li
Li, Shitong
Luo, Fang
Xiang, Zhou
Ding, Qunfang
Relationship between comorbidities and treatment decision-making in elderly hip fracture patients
title Relationship between comorbidities and treatment decision-making in elderly hip fracture patients
title_full Relationship between comorbidities and treatment decision-making in elderly hip fracture patients
title_fullStr Relationship between comorbidities and treatment decision-making in elderly hip fracture patients
title_full_unstemmed Relationship between comorbidities and treatment decision-making in elderly hip fracture patients
title_short Relationship between comorbidities and treatment decision-making in elderly hip fracture patients
title_sort relationship between comorbidities and treatment decision-making in elderly hip fracture patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825646/
https://www.ncbi.nlm.nih.gov/pubmed/30993661
http://dx.doi.org/10.1007/s40520-019-01134-5
work_keys_str_mv AT weijinxing relationshipbetweencomorbiditiesandtreatmentdecisionmakinginelderlyhipfracturepatients
AT zengli relationshipbetweencomorbiditiesandtreatmentdecisionmakinginelderlyhipfracturepatients
AT lishitong relationshipbetweencomorbiditiesandtreatmentdecisionmakinginelderlyhipfracturepatients
AT luofang relationshipbetweencomorbiditiesandtreatmentdecisionmakinginelderlyhipfracturepatients
AT xiangzhou relationshipbetweencomorbiditiesandtreatmentdecisionmakinginelderlyhipfracturepatients
AT dingqunfang relationshipbetweencomorbiditiesandtreatmentdecisionmakinginelderlyhipfracturepatients