Changes in Corneal Asphericity after MyoRing Implantation in Moderate and Severe Keratoconus

PURPOSE: To evaluate the effect of MyoRing implantation on corneal asphericity in moderate and severe keratoconus (KCN). METHODS: This cross-sectional observational study comprised 32 eyes of 28 patients with KCN, who had femtosecond-assisted MyoRing corneal implantation. The primary outcome measures were preoperative and six-month postoperative corneal asphericity in 6-, 7-, 8-, 9-, and 10-mm optical zones in the superior, inferior, nasal, temporal, and central areas. The secondary outcome measures included uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), manifest refraction, thinnest location value, and keratometry readings. RESULTS: A significant improvement in the UDVA and CDVA was observed six months after the surgery (P [Formula: see text] 0.001) with a significant reduction in the spherical (4.67 diopters (D)) and cylindrical (2.19 D) refractive errors. A significant reduction in the corneal asphericity in all the optical zones and in the superior, inferior, nasal, temporal, and central areas was noted (P [Formula: see text] 0.001). The mean thickness at the thinnest location of the cornea decreased from 437.15 [Formula: see text] 30.69 to 422.81 [Formula: see text] 36.91 μm. A significant corneal flattening was seen. The K1, K2, and Km changes were 5.32 D, 7 D, and 6.17 D, respectively (P [Formula: see text] 0.001). CONCLUSION: MyoRing implantation is effective for improving corneal asphericity in patients with KCN. It allows successful corneal remodeling and provides a significant improvement in UDVA, CDVA, and refractive errors.