Cargando…

Prevalence and risk factors for painful diabetic neuropathy in secondary healthcare in Qatar

AIMS/INTRODUCTION: Painful diabetic peripheral neuropathy (PDPN) has a significant impact on the patient's quality of life. The prevalence of PDPN in the Middle East and North Africa region has been reported to be almost double that of populations in the UK. We sought to determine the prevalenc...

Descripción completa

Detalles Bibliográficos
Autores principales: Ponirakis, Georgios, Elhadd, Tarik, Chinnaiyan, Subitha, Dabbous, Zeinab, Siddiqui, Mashhood, Al‐muhannadi, Hamad, Petropoulos, Ioannis, Khan, Adnan, Ashawesh, Khaled AE, Dukhan, Khaled MO, Mahfoud, Ziyad R, Murgatroyd, Christopher, Slevin, Mark, Malik, Rayaz A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825939/
https://www.ncbi.nlm.nih.gov/pubmed/30860314
http://dx.doi.org/10.1111/jdi.13037
_version_ 1783464981309685760
author Ponirakis, Georgios
Elhadd, Tarik
Chinnaiyan, Subitha
Dabbous, Zeinab
Siddiqui, Mashhood
Al‐muhannadi, Hamad
Petropoulos, Ioannis
Khan, Adnan
Ashawesh, Khaled AE
Dukhan, Khaled MO
Mahfoud, Ziyad R
Murgatroyd, Christopher
Slevin, Mark
Malik, Rayaz A
author_facet Ponirakis, Georgios
Elhadd, Tarik
Chinnaiyan, Subitha
Dabbous, Zeinab
Siddiqui, Mashhood
Al‐muhannadi, Hamad
Petropoulos, Ioannis
Khan, Adnan
Ashawesh, Khaled AE
Dukhan, Khaled MO
Mahfoud, Ziyad R
Murgatroyd, Christopher
Slevin, Mark
Malik, Rayaz A
author_sort Ponirakis, Georgios
collection PubMed
description AIMS/INTRODUCTION: Painful diabetic peripheral neuropathy (PDPN) has a significant impact on the patient's quality of life. The prevalence of PDPN in the Middle East and North Africa region has been reported to be almost double that of populations in the UK. We sought to determine the prevalence of PDPN and its associated factors in type 2 diabetes mellitus patients attending secondary care in Qatar. MATERIALS AND METHODS: This was a cross‐sectional study of 1,095 participants with type 2 diabetes mellitus attending Qatar's two national diabetes centers. PDPN and impaired vibration perception on the pulp of the large toes were assessed using the Douleur Neuropathique en 4 questionnaire with a cut‐off ≥4 and the neurothesiometer with a cut‐off ≥15 V, respectively. RESULTS: The prevalence of PDPN was 34.5% (95% confidence interval [CI] 31.7–37.3), but 80% of these patients had not previously been diagnosed or treated for this condition. Arabs had a higher prevalence of PDPN compared with South Asians (P < 0.05). PDPN was associated with impaired vibration perception adjusted odds ratio (AOR) 4.42 (95% CI 2.92–6.70), smoking AOR 2.43 (95% CI 1.43–4.15), obesity AOR 1.74 (95% CI 1.13–2.66), being female AOR 1.65 (95% CI: 1.03–2.64) and duration of diabetes AOR 1.08 (95% CI 1.05–1.11). Age, poor glycemic control, hypertension, physical activity and proteinuria showed no association with PDPN. CONCLUSIONS: PDPN occurs in one‐third of type 2 diabetes mellitus patients attending secondary care in Qatar, but the majority have not been diagnosed. Arabs are at higher risk for PDPN. Impaired vibration perception, obesity and smoking are associated with PDPN in Qatar.
format Online
Article
Text
id pubmed-6825939
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-68259392019-11-07 Prevalence and risk factors for painful diabetic neuropathy in secondary healthcare in Qatar Ponirakis, Georgios Elhadd, Tarik Chinnaiyan, Subitha Dabbous, Zeinab Siddiqui, Mashhood Al‐muhannadi, Hamad Petropoulos, Ioannis Khan, Adnan Ashawesh, Khaled AE Dukhan, Khaled MO Mahfoud, Ziyad R Murgatroyd, Christopher Slevin, Mark Malik, Rayaz A J Diabetes Investig Articles AIMS/INTRODUCTION: Painful diabetic peripheral neuropathy (PDPN) has a significant impact on the patient's quality of life. The prevalence of PDPN in the Middle East and North Africa region has been reported to be almost double that of populations in the UK. We sought to determine the prevalence of PDPN and its associated factors in type 2 diabetes mellitus patients attending secondary care in Qatar. MATERIALS AND METHODS: This was a cross‐sectional study of 1,095 participants with type 2 diabetes mellitus attending Qatar's two national diabetes centers. PDPN and impaired vibration perception on the pulp of the large toes were assessed using the Douleur Neuropathique en 4 questionnaire with a cut‐off ≥4 and the neurothesiometer with a cut‐off ≥15 V, respectively. RESULTS: The prevalence of PDPN was 34.5% (95% confidence interval [CI] 31.7–37.3), but 80% of these patients had not previously been diagnosed or treated for this condition. Arabs had a higher prevalence of PDPN compared with South Asians (P < 0.05). PDPN was associated with impaired vibration perception adjusted odds ratio (AOR) 4.42 (95% CI 2.92–6.70), smoking AOR 2.43 (95% CI 1.43–4.15), obesity AOR 1.74 (95% CI 1.13–2.66), being female AOR 1.65 (95% CI: 1.03–2.64) and duration of diabetes AOR 1.08 (95% CI 1.05–1.11). Age, poor glycemic control, hypertension, physical activity and proteinuria showed no association with PDPN. CONCLUSIONS: PDPN occurs in one‐third of type 2 diabetes mellitus patients attending secondary care in Qatar, but the majority have not been diagnosed. Arabs are at higher risk for PDPN. Impaired vibration perception, obesity and smoking are associated with PDPN in Qatar. John Wiley and Sons Inc. 2019-04-02 2019-11 /pmc/articles/PMC6825939/ /pubmed/30860314 http://dx.doi.org/10.1111/jdi.13037 Text en © 2019 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Articles
Ponirakis, Georgios
Elhadd, Tarik
Chinnaiyan, Subitha
Dabbous, Zeinab
Siddiqui, Mashhood
Al‐muhannadi, Hamad
Petropoulos, Ioannis
Khan, Adnan
Ashawesh, Khaled AE
Dukhan, Khaled MO
Mahfoud, Ziyad R
Murgatroyd, Christopher
Slevin, Mark
Malik, Rayaz A
Prevalence and risk factors for painful diabetic neuropathy in secondary healthcare in Qatar
title Prevalence and risk factors for painful diabetic neuropathy in secondary healthcare in Qatar
title_full Prevalence and risk factors for painful diabetic neuropathy in secondary healthcare in Qatar
title_fullStr Prevalence and risk factors for painful diabetic neuropathy in secondary healthcare in Qatar
title_full_unstemmed Prevalence and risk factors for painful diabetic neuropathy in secondary healthcare in Qatar
title_short Prevalence and risk factors for painful diabetic neuropathy in secondary healthcare in Qatar
title_sort prevalence and risk factors for painful diabetic neuropathy in secondary healthcare in qatar
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825939/
https://www.ncbi.nlm.nih.gov/pubmed/30860314
http://dx.doi.org/10.1111/jdi.13037
work_keys_str_mv AT ponirakisgeorgios prevalenceandriskfactorsforpainfuldiabeticneuropathyinsecondaryhealthcareinqatar
AT elhaddtarik prevalenceandriskfactorsforpainfuldiabeticneuropathyinsecondaryhealthcareinqatar
AT chinnaiyansubitha prevalenceandriskfactorsforpainfuldiabeticneuropathyinsecondaryhealthcareinqatar
AT dabbouszeinab prevalenceandriskfactorsforpainfuldiabeticneuropathyinsecondaryhealthcareinqatar
AT siddiquimashhood prevalenceandriskfactorsforpainfuldiabeticneuropathyinsecondaryhealthcareinqatar
AT almuhannadihamad prevalenceandriskfactorsforpainfuldiabeticneuropathyinsecondaryhealthcareinqatar
AT petropoulosioannis prevalenceandriskfactorsforpainfuldiabeticneuropathyinsecondaryhealthcareinqatar
AT khanadnan prevalenceandriskfactorsforpainfuldiabeticneuropathyinsecondaryhealthcareinqatar
AT ashaweshkhaledae prevalenceandriskfactorsforpainfuldiabeticneuropathyinsecondaryhealthcareinqatar
AT dukhankhaledmo prevalenceandriskfactorsforpainfuldiabeticneuropathyinsecondaryhealthcareinqatar
AT mahfoudziyadr prevalenceandriskfactorsforpainfuldiabeticneuropathyinsecondaryhealthcareinqatar
AT murgatroydchristopher prevalenceandriskfactorsforpainfuldiabeticneuropathyinsecondaryhealthcareinqatar
AT slevinmark prevalenceandriskfactorsforpainfuldiabeticneuropathyinsecondaryhealthcareinqatar
AT malikrayaza prevalenceandriskfactorsforpainfuldiabeticneuropathyinsecondaryhealthcareinqatar