Mecp2 Deletion from Cholinergic Neurons Selectively Impairs Recognition Memory and Disrupts Cholinergic Modulation of the Perirhinal Cortex

Rett Syndrome is a neurological disorder caused by mutations in the gene encoding methyl CpG binding protein 2 (MeCP2) and characterized by severe intellectual disability. The cholinergic system is a critical modulator of cognitive ability and is affected in patients with Rett Syndrome. To better un...

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Detalles Bibliográficos
Autores principales: Ballinger, Elizabeth C., Schaaf, Christian P., Patel, Akash J., de Maio, Antonia, Tao, Huifang, Talmage, David A., Zoghbi, Huda Y., Role, Lorna W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2019
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825959/
https://www.ncbi.nlm.nih.gov/pubmed/31562178
http://dx.doi.org/10.1523/ENEURO.0134-19.2019

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